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Tropical Journal of Obstetrics and Gynaecology

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Volume 19, Number 1, April 2002
Abstracts

Hypoxaemia During Gynaecological Laparoscopy Under Local Anaesthesia and Sedation.

Simbo D. Amanor-Boadu1, Adesina Oladokun2, Ayodele O. Arowojolu2 and Akin-Tunde Odukogbe2

Departments of 1Anaesthesia and 2Obstetrics & Gynaecology, College of Medicine, University College Hospital, Ibadan, Nigeria.

Abstract

Context: Laparoscopy is a procedure with significant potential for hypoxaemia due to the respiratory changes accompanying pneumoperitoneum and the Trendelenberg position used. Hypoxaemia may be critical when the procedure is conducted under local anaesthesia and conscious sedation.

Objective: The aim of this study was to determine the extent to which hypoxaemic episodes occurred during gynaecological laparoscopy performed under conscious sedation.

Study Design, Setting and Subjects: This was a cross-sectional study of consecutive patients undergoing investigative laparoscopy at the University College Hospital, Ibadan. Informed consent was obtained from patients and they were prepared for the procedure on a day-care basis. The demographic data and vital signs were recorded. Pentazocine (60 mg) and diazepam (10 mg) were administered intravenously.

Main Outcome Measures: The respiratory rate, pulse rate, blood pressure and oxygen saturation were measured pre-, intra-, and post-operatively.

Results: Thirty-two patients were recruited into the study. They had no intercurrent medical diseases. Mean age was 33 years (SD 4.2) and mean Body Mass Index (BMI) was 24.49 (SD 2.87). Oxygen saturation was normal in every patient pre-sedation. Post sedation, 19 (54%) of the patients desaturated in the period before surgical stimulation. Oxygen saturation remained between 90% and 95% in 6 (19 %) patients intraoperatively. There were no postoperative episodes of desaturation. There was no correlation between the BMI and the degree of desaturation.

Conclusion: A significant degree of desaturation occurs during gynaecologic laparoscopy under pentazocine and diazepam sedation. It is recommended that oxygen should be administered to all patients during the procedure.

Key Words: Gynaecological Laparoscopy, Sedation, Hypoxaemia. [Trop J Obstet Gynaecol, 2002, 19: 4-7].

 

 

Clinical Correlates of Unexplained Infertility in Southeastern Nigeria.

Joseph I. Ikechebelu1, J.I. Brian-D Adinma1, Sylvester G. Ikegwuonu2 and Emeka F. Orie1.

Department of Obstetrics and Gynaecology, 1Nnamdi Azikiwe University Teaching Hospital, P.M.B. 5025, Nnewi, Nigeria and 2Silgrey Royal Hospital, Awka, Nigeria.

Abstract:

Context: In the absence of any obvious aetiological factor, a couple is said to have unexplained infertility. It is desirable to identify factors associated with unexplained infertility in this environment and to ascertain if there is a causal relationship between infertility and uterine leiomyomata.

Objective: The study is aimed at identifying clinical factors associated with unexplained infertility and determining if there is any difference in the prevalence of uterine fibroids between women for whom a cause of infertility is identifiable and those with unexplained infertility.

Study Methods: The records of infertility patients from our clinics at Nnewi and Awka were examined for the identifiable causes of infertility and the presence of uterine fibroids.

Results: The cause of infertility was obvious in 279 (89%) of the 314 couples that completed their evaluation while 35 couples (11%) had unexplained infertility. The type of infertility (primary or secondary) had no influence on whether the aetiology is identified or not. However, increasing parity and duration of infertility is significantly associated with an identifiable aetiology. Uterine leiomyomata were present in 61 (19%) of the 314 infertile women studied. Fifty (18%) of the women who had an identifiable cause for their infertility had fibroids compared to 11 (31%) of the women with unexplained infertility (P < 0.005).

Conclusion: Unexplained infertility is less common with increasing parity and duration of infertility. Uterine fibroids are more common in women with unexplained infertility. Myomectomy in these women may offer a greater chance of achieving conception.

Key Words: Infertility, Uterine Leiomyomata, Myomectomy. [Trop J Obstet Gynaecol, 2002, 19: 8-11].

 

Effectiveness of Information, Education and Communication (IEC) on the Public Acceptability of Unsafe Abortion Solutions.

Ishaq F Abdul1, Olayinka R Balogun1, Momoh Anate1, Yusuf M Kasim1, Mohammed J Saka1 and Yusuf S Oganija2.

1Department of Obstetrics and Gynaecology, University of Ilorin Teaching Hospital, Maternity Wing, P.M.B 1339 and 2Department of Community Health and Epidemiology, University of Ilorin Teaching Hospital, P.M.B 1459, Ilorin, Nigeria .

Abstract

Context: Public health measures suggested to curb the menace of unsafe abortions in developing countries include liberalization of abortion law, family life education and family planning. However public acceptability of these solution options are poor.

Objective: To examine the efficacy of information, education and communication (IEC) on the public acceptability of unsafe abortion solution options of contraception, family life education including sex education and liberalization of abortion laws. Our aim was to use IEC to improve public acceptability of the recommended solutions.

Methods: Trained questionnaire administrators interviewed randomly selected civil servants in Ilorin, Nigeria to asses the level of their acceptability of the various options. There were 95 respondents for the baseline interviews and 93 respondents for the post IEC interviews. The responses were compared pre- and post-IEC to assess the effectiveness of the IEC.

Results: Contraception for adults was the most acceptable solution to the public both pre- and post-IEC, the acceptability doubling (46.3% to 93.4%) after IEC. Contraception for adolescents, and family life education showed appreciable improved acceptability post IEC (25.3% to 40.2% and 40% to 67.4%) respectively Liberalization of abortion law also appreciated marginally in the amount of yes answers (14.8% to 18.5%). Ironically, the percentage of rejecters also appreciated from 78.9% to 79.3%, giving a very weak correlation coefficient of 0.42.

Conclusion: IEC is effective in improving public acceptability of unsafe abortion solutions. The need for an extension and sustenance of this intervention strategy to all segments of the society for effective advocacy is an imperative

Key Words: Unsafe Abortions, Information, Counselling, Education [Trop J Obstet Gynaecol, 2002, 19: 12-16].

 

Obstetric Performance of Nigerian Obese Parturients

Oladapo O. Olayemi, Celestine O Umuerri and Christopher O. Aimakhu.

Department of Obstetrics and Gynaecology, University College Hospital, P. M. B 5117, Ibadan, Nigeria.

Abstract

Context: Obesity constitutes a health hazard and the greater the degree of obesity, the greater the health risks. This is especially so in obstetric practice where complications of pregnancy are reportedly greater in obese patients.

Objectives: To determine the prevalence of obesity and to compare the outcome of pregnancy between obese and non-obese patients.

Material and Methods: A review of the case records over a five-year period at a Nigerian teaching hospital to identify obese patients who delivered babies was done. Outcome of pregnancy in the 205 obese patients identified (using a weight of 90 kg and above as cut-off) was compared with 206 controls.

Results: The incidence of obesity in pregnancy was 7.4%. The obese patients were older than the controls (p<0.05). There was no significant difference in socio-economic status in the two groups. More of the obese patients were multiparous (p <0.01). Preeclampsia was significantly more common in the obese group (p<0.001). The caesarean section rate was also higher in the obese group (p<0.001). The incidence of fetal macrosomia was higher in the obese group (p<0.001).

Conclusion: Obesity increased the risk of preeclampsia and fetal macrosomia and operative deliveries. The risk of birth asphyxia and perinatal mortality were not increased by obesity.

Key Words: Obesity, Parturient, Maternal, Neonatal, Outcome. [Trop J Obstet Gynaecol, 2002, 19: 17-20].

 

HIV in Pregnancy: Experience at Abeokuta, Nigeria.

A. Olubukola Fawole1, Oladapo S. Sotiloye1, Kehinde I. Hunyinbo1, Olufunmilayo I. Fawole2,

Ayodele O. Oladimeji1, Adetoye Durodola1, Sunday I. Omisakin1, Abiodun O. Bale1, Usen A. Udo3 and E. Oladipo Otolorin4.

1Department of Obstetrics and Gynaecology, Federal Medical Centre (FMC), Abeokuta, Nigeria; 2Department of Epidemiology, Medical Statistics and Environmental Health, College of Medicine, University of Ibadan, Ibadan, Nigeria; 3Department of Pathology, FMC, Abeokuta, Nigeria and 4Regional Centre for Quality of Health Care, Makerere University, Kampala, Uganda.

Abstract

Background: The human immunodeficiency virus (HIV) pandemic remains a major threat to public health. Measures to minimize mother to child transfusion remain a major focus of research.

Objectives: To determine the prevalence of HIV in pregnancy in our obstetric clinic population and evaluate the effects of HIV infection on the course and outcome of pregnancy.

Materials & Methods: A case-control study of all HIV-positive pregnant women who delivered at the Federal Medical Centre, Abeokuta between January, 1997 and June, 2000. Selected characteristics including age, parity, gestational age at booking, weight gain in pregnancy, duration of pregnancy and the infants’ characteristics were compared between seropositive and negative women.

Results: Sixteen women had HIV infection among a total of 2,442 women booked during the study period. The prevalence of HIV infection in pregnancy was 0.7%. Following diagnosis, eight of the HIV positive women defaulted from ante-natal care None opted for anti-retroviral therapy. There were no statistically significant differences in the haematocrit at booking (p=0.9), the weight gain in pregnancy (p=0.2), birth-weights between the two groups. All the women had vaginal deliveries. There were significant differences in the infants’ Apgar scores and perinatal mortality rates were higher in the HIV positive group. All the mothers chose to breastfeed their infants.

Conclusion: HIV infection in this population is associated with birth asphyxia and a high perinatal mortality rate. The survivors are also at great risk of vertical transmission during breast-feeding.

Key Words: HIV, Pregnancy, Vertical Transmission, Birth Asphyxia. [Trop J Obstet Gynaecol, 2002, 19: 21-24].

 

Birth Asphyxia, Perinatal and Maternal Mortality Associated With Caesarean Section

Fidelis O. Njokanma, Matthias T.C. Egri-Okwaji, Chikezie A. Nwokoro, Taiwo Orebamjo and Godwin C.E. Okeke

Havana Specialist Hospital, 115 Akerele Street, Surulere, Lagos

Abstract:

Context: Caesarean section is sometimes required to improve maternal and neonatal outcome but adverse results occasionally occur. A review of associated adverse consequences is useful in identifying areas requiring improvement.

Objective: To study the association between caesarean delivery and maternal/fetal outcome.

Study Design, Setting and Subjects: A descriptive, fifteen-year report (1983 through 1997) from a private hospital in Lagos, Nigeria. The subjects were mothers delivered by caesarean section and their singleton babies.

Main Outcome Measures: Perinatal asphyxia rate, stillbirth rate, early neonatal death rate, maternal mortality rate.

Results: There were 1140 total deliveries. There were 240 cases (21.2%) of birth asphyxia and 16 early neonatal deaths (14.4/1000) among the 1113 live deliveries. There were 27 stillbirths (33.68/1000) and 3 maternal deaths (2.63/1000), all from emergency caesarean deliveries. Preterm delivery was associated with higher asphyxia rate (37.3% vs 22.8%, p < 0.05), while elective section had a lower asphyxia rate than emergency surgery (10.8% vs 24.3%, p < 0.05). Non-booked cases had significantly higher asphyxia rate (22.8% vs 3.9%), five-fold early stillbirth rate (95.54/1000 vs 18.24/1000), four-fold early neonatal death rate (42.25/1000 vs 10.40/1000) and a 12-fold higher maternal mortality rate (12.74/1000 vs 1.02/1000). Antepartum haemorrhage and hypertensive disease were the indications for surgery most frequently associated with perinatal mortality.

Conclusions: The hazards of caesarean section are worse with emergency surgery but significant asphyxia occurs even following elective section. Early appropriate referral of high-risk cases will help to reduce perinatal/maternal morbidity and mortality.

Key Words: Caesarean Section, Maternal, Neonatal, Mortality, Birth Asphyxia [Trop J Obstet Gynaecol 2002; 19: 25-29].

 

Case Reporting of Maternal Deaths in Nigeria: A Survey of Obstetricians

Vincent O. Otoide

Department of Obstetrics and Gynaecology, University of Benin Teaching Hospital, P.M.B 1111, Benin-City, Edo State, Nigeria.

Abstract

Context: Accurate data on maternal deaths is of public health concern. In Nigeria, a country with one of the highest rates of maternal mortality in the world, little is known of how such information is managed.

Objective: To determine case reporting of maternal deaths among Nigerian obstetricians and make policy recommendations on improving the reporting.

Study Design: A descriptive study was conducted among Nigerian obstetricians attending an annual national conference. A structured questionnaire was used in eliciting relevant information.

Main Outcome Measure: Rate of case reporting of maternal deaths.

Results: One hundred and five obstetricians were involved in the study. Nearly 42% affirmed case reporting of maternal deaths at their hospital of practice. More than 54% of respondents (49.5% of study population) did not routinely report cases. There was lack of uniformity in the processes and procedures for case reporting.

Conclusion: The majority of practicing obstetricians in Nigeria are not involved in routine case reporting of maternal deaths. Strategies for a uniform approach are suggested.

Key Words: Maternal Deaths, Case Reporting, Autopsy, Nigeria. [Trop J Obstet Gynaecol, 2002, 19: 30-31].

 

Maternal Factors Associated With Early Spontaneous Singleton Preterm Delivery in Nigeria

Olugbenga A. Mokuolu1, Ishaq F. Abdul2 and Omotayo Adesiyun1

Departments of Paediatrics 1, and Obstetrics & Gynaecology 2, University of Ilorin Teaching Hospital, Ilorin, Nigeria

Abstract

Background: Knowledge of the maternal factors predisposing to preterm deliveries should affect the anticipatory care of mothers at risk of delivering preterm babies and improve perinatal outcome.

Objective: To determine the maternal socio-biological characteristics associated with the delivery of early spontaneous singleton preterm babies in a sample of Nigerian Women.

Methods: The study was conducted at a teaching hospital in the Guinea savannah belt of Nigeria. Two groups of patients were recruited. Group A consisted of women who delivered babies prior to a gestational age of ² 34 weeks, while Group B were mothers who delivered at 37 or more weeks. Data collected on each subject included maternal post-partum weight, height, obstetric data and social characteristics.

Results: A total of 171 mothers were studied; 69 in Group A and 102 in Group B. There was no significant difference between the socio-demographic profiles of the two groups. Factors significantly associated with preterm delivery were body mass index (BMI) ² 20.0 [Odds Ratio (OR) 14.6; 95% CI: 3.2-66.1]; previous preterm delivery [OR: 4.5; 95% CI: 1.5-13.3]; parity 1-2 [OR: 2.1; 95% CI: 1.1-4.0] and previous abortion [OR: 1.6; 95% CI: 1.2-2.4]. These associations were still demonstrable after adjusting for confounding variables, with BMI being the strongest determinant of preterm delivery. Maternal height alone and previous uterine curettage were not significantly associated with preterm delivery.

Conclusion: Low BMI, low parity, previous preterm delivery and previous abortions were the maternal factors associated with early spontaneous singleton preterm delivery in a sample of Nigerian women.

Key Words: Maternal, Labour, Preterm Births, Prematurity, Perinatal [Trop J Obstet Gynaecol, 2002, 19: 32-35]

 

Determinants of Perinatal Mortality in Twins at Ibadan

Oladapo O. Olayemi, Adetunji R. Adeniji and Christopher O. Aimakhu.

Department of Obstetrics and Gynaecology, University College Hospital, P. M. B 5117, Ibadan, Nigeria.

Abstract

Context: Twinning being a very important high-risk condition in our environment requires detailed study. There are several studies reviewing factors in twin perinatal mortality in our environment but there is a need to ascertain the relative contributions of each of these factors.

Objectives: To assess the relative contributions of maternal and fetal factors to perinatal mortality in twins.

Materials and Methods: Data was extracted from the birth register of a Nigerian tertiary health institution to identify maternal and fetal factors associated with a higher risk of perinatal mortality.

Outcome Measures: Perinatal deaths among twin pairs (ranked).

Results: The twinning rate was 32.3/1000(3.2%). Risk of perinatal death had linear correlation with birth asphyxia (r = 0.412, p < 0.01), birth weight of the second twin (r = 0.358, p < 0.01), birth weight of the smaller twin (r = -0.344, p < 0.01), presence of birth weight discordance (r = 0.278, p < 0.01), gestational age at delivery (r = -0.211, p < 0.05), birth weights of first and larger twins (r = -0.275, p < 0.01) and (r = -0.206, p < 0.05) respectively. The maternal age and parity showed no significant correlation with risk of perinatal death.

Conclusion: Birth asphyxia was the greatest predictor of perinatal death in twins among the variables studied.

Key Words: Twins, Birthweight Discordance, Perinatal Mortality [Trop J Obstet Gynaecol, 2002, 19: 36-38].

 

Effects of Nutritional Status and Supplementation on Resumption of Menstruation Amongst Parturient Nigerian Women

Omobola A. Ogundahunsi1, Adegboyega O. Ketiku2, Adewale O. Sule-Odu3,

Tuminu A. Fakoya3 and Oluwakayode A. Dada4

1Departments of Chemical Pathology & Haematology and 3Obstetrics & Gynaecology, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria; 2Department of Human Nutrition, University of Ibadan, Ibadan, Nigeria; and 4Centre for Research in Reproductive Health, C/10 Cinema Road, Sagamu , Ogun State, Nigeria.

Abstract

Context: Breastfeeding patterns, ethnic variation and nutrition have been shown to influence the return of menstruation after childbirth, but the role played by nutritional status requires further elucidation, particularly in a place like Nigeria where undernutrition is common.

Objectives: To determine the effects of nutrition and breastfeeding pattern on the duration of lactational amenorrhoea in Nigerian women.

Subjects and Methods: Marginally malnourished mothers (162) were randomised into two groups [A & B] for comparison with a third group [C] of well-nourished mothers. Mothers in Group A (83 subjects) received supplements in the form of specially formulated biscuits while those in Group B (79 women) & Group C (85 women) received none. The subjects were visited 3 times a week to ensure compliance with the supplements and to collect information on breastfeeding pattern and duration of lactational amenorrhoea.

Results: There were no significant differences in the duration of postpartum amenorrhoea in the three groups of mothers, being 270, 220 and 234 days for Groups A, B and C respectively. Wide individual variations were observed in the duration of amenorrhoea in each group of mothers despite the fact that they generally had similar patterns of breastfeeding. The energy expenditure patterns in the supplemented and unsupplemented mothers were similar.

Conclusion: Nutritional status and supplementation do not seem to influence the duration of lactational amenorrhoea in this group of Nigerian women. Subtle physiological differences between individual women may account for the wide individual variations observed in the time of resumption of menstruation after childbirth in the subjects.

Key Words: Breastfeeding, Lactational Amenorrhoea, Nutritional Status, Menstruation. [Trop J Obstet Gynaecol, 2002, 19: 39-43].

 

The Use of the Foley Catheter in Controlling Severe Uterine Haemorrhage in Gynaecological

Practice.

Justus N. Eze, Gabriel C. Iloabachie and Hyacinth E. Onah

Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital (UNTH), Enugu.

Abstract:

Three patients with severe uterine bleeding were managed successfully by intracavitary insertion and distension of Foley catheter balloons. Blood transfusion was averted in the first patient and reduced to 2 units in the second, while imminent maternal death was prevented in the third case. The availability of the Foley catheter and minimal requirements for its use, coupled with lack of untoward effects in cases managed, make the procedure a useful one.

Key Words: Uterus, Haemorrhage, Foley Catheter. [Trop J Obstet Gynaecol, 2002, 19: 44-46]

 

Ruptured Uterus in a Primigravida: Case Report

P.C. Ibekwe

Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Enugu, Nigeria.

*Currently Consultant Obstetrician/Gynaecologist, Ebonyi State University Teaching Hospital, Abakaliki,Nigeria

Abstract

A case of ruptured uterus in a 30 year-old primigravida is presented. The patient went into labour at term and reported to a local maternity where it was discovered that the fetus had a breech presentation. The attending midwife decided to attempt an external cephalic version. Soon afterward, the patient developed generalized abdominal pains, dizziness and fainting attacks. Prompt referral, immediate resuscitation and urgent laparotomy saved the patient although it meant the end of her reproductive career.

Key Words: Uterus, Rupture, Haemorrhage, Primigravida. [Trop J Obstet Gynaecol, 2002, 19: 47-48]

 

 

Rupture of the Pregnant Uterus in an Unbooked Primigravida: a Case Report

Ernest O. Orji, Abiodun A. Dayo and Olasunkanmi O. Malomo

Department of Obstetrics and Gynaecology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.

Abstract

Uterine rupture is a life threatening complication in pregnancy in developing countries. While multiparity is a commonly associated factor, primigravida are said to be ‘immune’ to uterine rupture. We present a case of uterine rupture in an unbooked primigravida who had massive bolus doses of intravenous oxytocin in the presence of prolonged obstructed labour and pelvic contraction. Operative findings include a male fresh stillbirth weighing 3.8 kg. and a transverse uterine rupture at the lower segment. Peritoneal lavage and repair of the rupture without bilateral tubal ligation were done.

Key Words: Uterus, Rupture, Haemorrhage, Primigravida. [Trop J Obstet Gynaecol, 2002, 19: 49-50]

 

Congenital Thyrotoxicosis: a Case Report.

S.N. Ibeziako and N.K. Chukwudi

Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu, Nigeria.

Abstract

A case of a preterm neonate with congenital thyrotoxicosis is reported. Her mother had thyrotoxicosis which was diagnosed at 27 weeks gestation, and was treated with propranolol and carbimazole. The diagnosis of thyrotoxicosis in the neonate was confirmed by an elevated serum tri-iodo-thyronine (T3) level of 6.7 nmol/L, a thyroid stimulating hormone (TSH) level of less than 0.3 mu/L, and advanced bone age of between 3-6 months, at birth. The baby was treated with propranolol and Lugol’s iodine, with a favourable outcome.

Key Words: Thyrotoxicosis, Maternal, Congenital, Neonate [Trop J Obstet Gynaecol, 2002, 19: 51-53].